HRT.so
Thyroid Support
4.5 Rating
Oral tablet (daily, empty stomach)

Levothyroxine (T4)

The standard first-line treatment for hypothyroidism, providing synthetic T4 hormone to restore normal thyroid function.

Overview

Levothyroxine is a synthetic form of thyroxine (T4), the primary hormone produced by the thyroid gland. It is the most commonly prescribed thyroid medication worldwide and is considered the gold standard for treating hypothyroidism. The body converts T4 to the more active T3 as needed.

How It Works

Levothyroxine replaces the T4 that an underactive thyroid cannot adequately produce. Once absorbed, T4 enters cells where deiodinase enzymes convert it to T3 (the active form) as needed. This allows the body to regulate its own T3 levels naturally.

Benefits

Restores normal T4 levels
Reliable and well-studied
Once daily dosing
Multiple dose strengths
Affordable generic options
Long track record of safety

Potential Side Effects

Overmedication symptoms (anxiety, rapid heart rate)
Hair loss initially
Headache
Insomnia
Weight changes
Requires fasting before dose

Dosage Information

Starting dose is typically 25-50mcg daily, taken on an empty stomach 30-60 minutes before breakfast. Full replacement dose averages 1.6mcg per kg of body weight. Regular blood work guides dose adjustments.

Quick Facts

Administration

Oral tablet (daily, empty stomach)

Rating

4.5 / 5.0

Category

Thyroid Support

Common Symptoms

Hypothyroidism
Fatigue
Weight gain
Cold intolerance

Common Questions

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